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Merck

CCNT1

cyclin T1

别名:
CCNT, CYCT1, HIVE1
物种:
UniProtKB ID:
基因ID:
  • Human(904) Summary: This gene encodes a member of the highly conserved cyclin C subfamily. The encoded protein tightly associates with cyclin-dependent kinase 9, and is a major subunit of positive transcription elongation factor b (p-TEFb). In humans, there are multiple forms of positive transcription elongation factor b, which may include one of several different cyclins along with cyclin-dependent kinase 9. The complex containing the encoded cyclin and cyclin-dependent kinase 9 acts as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and is both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner are also involved in triggering transcript elongation through phosphorylation of the carboxy-terminal domain of the largest RNA polymerase II subunit. Overexpression of this gene is implicated in tumor growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]
  • Mouse(12455) cyclin T1
  • Rat(315291) cyclin T1
  • Zebrafish(334465) cyclin T1
  • dog(486564) cyclin T1
  • chicken(100859215) cyclin T1
  • sheep(101106415) cyclin T1
  • domestic cat(101090703) cyclin T1
  • cow(407194) cyclin T1
  • naked mole-rat(101700254) cyclin T1
  • Horse(100033893) cyclin T1
  • domestic guinea pig(100731674) cyclin T1
  • Domestic Rabbit(100352150) cyclin T1
  • Goat(100860835) cyclin T1

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Antibodies

货号
说明
物种反应性
应用
Anti-CCNT1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry

western blot
Anti-CCNT1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
western blot
Anti-CCNT1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
immunofluorescence
western blot
Anti-Cyclin T1 Antibody, serum, from sheep,
物种反应性
human, mouse
应用
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human CCNT1,
物种
human
MISSION® esiRNA, targeting mouse Ccnt1,
物种
mouse