- Unravelling pathways downstream Sox6 induction in K562 erythroid cells by proteomic analysis.
Unravelling pathways downstream Sox6 induction in K562 erythroid cells by proteomic analysis.
Scientific reports (2017-10-28)
Gloria Barbarani, Antonella Ronchi, Margherita Ruoppolo, Lucia Santorelli, Robert Steinfelder, Sudharshan Elangovan, Cristina Fugazza, Marianna Caterino
PMID29074889
ABSTRACT
The Sox6 transcription factor is crucial for terminal maturation of definitive red blood cells. Sox6-null mouse fetuses present misshapen and nucleated erythrocytes, due to impaired actin assembly and cytoskeleton stability. These defects are accompanied with a reduced survival of Sox6
MATERIALS
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Sigma-Aldrich
Anti-U2AF65 antibody, Mouse monoclonal, clone MC3, purified from hybridoma cell culture