KN-62

Synonym(s):

(S)-5-Isoquinolinesulfonic acid 4-[2-[(5-isoquinolinylsulfonyl)methylamino]-3-oxo-3-(4-phenyl-1-piperazinyl)propyl]phenyl ester, 1-[N,O-bis(5-Isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenylpiperazine, KN-62

Empirical Formula (Hill Notation):

C₃₈H₃₅N₅O₆S₂

CAS Number:

127191-97-3

Molecular Weight:

721.84

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bioactive small molecules (2)

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I2142

KN-62, ≥95%, powder

422706

KN-62, A cell-permeable, reversible, and selective inhibitor of CaM kinase II (K_i = 900 nM for rat brain CaM kinase II) that binds directly to the calmodulin binding site of the enzyme.