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SAB2501178

Sigma-Aldrich

Anti-PNPLA3 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-ADPN, Anti-C22orf20, Anti-iPLA(2)ε, patatin-like phospholipase domain containing 3

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

goat

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

rat, mouse, human

technique(s)

immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... PNPLA3(80339)

General description

Patatin like phospholipase domain containing 3 (PNPLA3) is part of the patatin-like phospholipase family. This transmembrane lipase is made up of 481 amino acids. The gene encoding PNPLA3 is localized on human chromosome 22q13.31.

Immunogen

Peptide with sequence EHDICPKVKSTN, from the internal region of the protein sequence according to NP_473429.2.

Biochem/physiol Actions

Patatin like phospholipase domain containing 3 (PNPLA3) is a triglyceride hydrolase. It has been associated with hepatic steatosis.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Genetic Polymorphisms of the Human PNPLA3 Gene Are Strongly Associated with Severity of Non-Alcoholic Fatty Liver Disease in Japanese
Takahisa Kawaguchi
PLoS ONE (2012)
Physical activity and sedentary behavior can modulate the effect of the PNPLA3 variant on childhood NAFLD: a case-control study in a Chinese population.
Wang S
BMC Medical Genetics (2016)
Association of patatin-like phospholipase domain-containing protein 3 gene polymorphisms with susceptibility of nonalcoholic fatty liver disease in a Han Chinese population.
Song G
Medicine (2016)

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