BP725

Alverine citrate

British Pharmacopoeia (BP) Reference Standard

• Synonym(s): Alverine citrate salt, N-Ethyl-3,3′-diphenyldipropylamine, NSC 35459
• Empirical Formula (Hill Notation): C₂₀H₂₇N · C₆H₈O₇
• CAS Number: 5560-59-8
• Molecular Weight: 473.56
• MDL number: MFCD00035086
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: alverine
• form: crystalline powder
• shelf life: limited shelf life, expiry date on the label
• manufacturer/tradename: BP
• application(s): pharmaceutical; pharmaceutical small molecule
• format: neat
• SMILES string: OC(=O)CC(O)(CC(O)=O)C(O)=O.CCN(CCCc1ccccc1)CCCc2ccccc2
• InChI: 1S/C20H27N.C6H8O7/c1-2-21(17-9-15-19-11-5-3-6-12-19)18-10-16-20-13-7-4-8-14-20;7-3(8)1-6(13,5(11)12)2-4(9)10/h3-8,11-14H,2,9-10,15-18H2,1H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
• InChI key: RYHCACJBKCOBTJ-UHFFFAOYSA-N
• Gene Information: human ... HNF4A(3172) , HTR1A(3350)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Alverine citrate BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Alverine Capsules

Used for studies of pharmacological activity including:

• Synergism with fluconazole against Saccharomyces cerevisiae and Candida albicans
• Efficacy of combination with simeticone on abdominal pain associated with irritable bowel syndrome
• Nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis
• Drug effects viewed from a signal transduction network perspective
• Enhanced cytotoxic effect of proteasome inhibitor MG132
• Mechanism of action on phasic smooth muscles

Packaging

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Other Notes

Sales restrictions may apply.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable