STAT1
signal transducer and activator of transcription 1, 91kDa
Synonyms:
CANDF7, ISGF-3, STAT91
Species:
Human STAT1 (6772), Mouse Stat1 (20846), Rat Stat1 (25124), dog STAT1 (488449), sheep STAT1 (100307049), cow STAT1 (510814), Domestic Rabbit STAT1 (100343893), domestic guinea pig Stat1 (100724708), naked mole-rat Stat1 (101718902), chicken STAT1 (424044)
UniProtKB ID:
Gene ID:
- Human(6772) Summary: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
- Mouse(20846) signal transducer and activator of transcription 1
- Rat(25124) signal transducer and activator of transcription 1
- dog(488449) signal transducer and activator of transcription 1, 91kDa
- sheep(100307049) signal transducer and activator of transcription 1, 91kDa
- cow(510814) signal transducer and activator of transcription 1, 91kDa
- Domestic Rabbit(100343893) signal transducer and activator of transcription 1, 91kDa
- domestic guinea pig(100724708) signal transducer and activator of transcription 1, 91kDa
- naked mole-rat(101718902) signal transducer and activator of transcription 1, 91kDa
- chicken(424044) signal transducer and activator of transcription 1, 91kDa
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-STAT1 Antibody, CT, Upstate®, from rabbit,
Species Reactivity
human, mouse
Application
electrophoretic mobility shift assay
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-phospho-STAT1 (Tyr701) Antibody, Upstate®, from rabbit,
Species Reactivity
chicken, human, mouse, rat
Application
western blot
Anti-phospho-STAT1 (Ser 727) Antibody, clone 12C5, clone 12C5, Upstate®, from mouse,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-STAT1-α Antibody, Chemicon®, from rabbit,
Species Reactivity
human, mouse
Application
immunoprecipitation (IP)
western blot
western blot
Anti-Phospho-Stat1 (Tyr701) Antibody, clone 5C9.2, clone 5C9.2, from mouse,
Species Reactivity
human, mouse, rat
Application
western blot