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Merck

RBBP4

retinoblastoma binding protein 4

Synonyms:
NURF55, RBAP48
Species:
UniProtKB ID:
Gene ID:
  • Human(5928) Summary: This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
  • Mouse(19646) retinoblastoma binding protein 4
  • Rat(313048) retinoblastoma binding protein 4
  • domestic cat(101101239) retinoblastoma binding protein 4
  • chicken(395658) retinoblastoma binding protein 4
  • cow(767940) retinoblastoma binding protein 4
  • naked mole-rat(101721843) retinoblastoma binding protein 4
  • dog(478149) retinoblastoma binding protein 4
  • domestic guinea pig(100725928) retinoblastoma binding protein 4
  • sheep(101112378) retinoblastoma binding protein 4

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-RBBP4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-RBBP4, (C-terminal) antibody produced in mouse, clone 4A5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot
Anti-RBBP4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-RBBP4 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti- RBBP4 antibody produced in rabbit, ,
Species Reactivity
Application
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
EZH2/SUZ12/RbAp48 human, recombinant, expressed in baculovirus infected Sf9 cells, ≥88% (SDS-PAGE),
Species
human
EZH2 /EED/SUZ12/RbAp48/AEBP2 human, recombinant, expressed in baculovirus infected Sf9 cells, ≥90% (SDS-PAGE),
Species
human
EZH2/EED/SUZ12/RbAp48 active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥90% (SDS-PAGE),
Species
human
EZH2 /EED/SUZ12/RbAp48/AEBP2 human, recombinant, expressed in baculovirus infected Sf9 cells, ≥90% (SDS-PAGE),
Species
human
EZH2 /EED/SUZ12/RbAp48/AEBP2 human, recombinant, expressed in baculovirus infected Sf9 cells, ≥90% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Rbbp4,
Species
mouse
MISSION® esiRNA, targeting human RBBP4,
Species
human