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Merck

NPL

N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)

Synonyms:
C112, C1orf13, NAL, NPL1
Species:
UniProtKB ID:
Gene ID:
  • Human(80896) Summary: This gene encodes a member of the N-acetylneuraminate lyase sub-family of (beta/alpha)(8)-barrel enzymes. N-acetylneuraminate lyases regulate cellular concentrations of N-acetyl-neuraminic acid (sialic acid) by mediating the reversible conversion of sialic acid into N-acetylmannosamine and pyruvate. A pseudogene of this gene is located on the short arm of chromosome 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
  • Mouse(74091) N-acetylneuraminate pyruvate lyase
  • Rat(304860) N-acetylneuraminate pyruvate lyase
  • Zebrafish(100148292) N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
  • chicken(429074) N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
  • dog(490313) N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
  • domestic cat(101091498) N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
  • cow(507597) N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
  • sheep(101104513) N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
  • domestic guinea pig(100734839) N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
  • naked mole-rat(101721787) N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-NPL antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Npl,
Species
mouse
MISSION® esiRNA, targeting human NPL,
Species
human