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Merck

MAPK3

mitogen-activated protein kinase 3

Synonyms:
ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK
Species:
UniProtKB ID:
Gene ID:
  • Human(5595) Summary: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, Jul 2008]
  • Mouse(26417) mitogen-activated protein kinase 3
  • Rat(50689) mitogen activated protein kinase 3
  • Zebrafish(399480) mitogen-activated protein kinase 3
  • domestic cat(101087958) mitogen-activated protein kinase 3
  • cow(531391) mitogen-activated protein kinase 3
  • Horse(100066173) mitogen-activated protein kinase 3
  • dog(479790) mitogen-activated protein kinase 3
  • sheep(101123008) mitogen-activated protein kinase 3
  • naked mole-rat(101702687) mitogen-activated protein kinase 3
  • domestic guinea pig(100725692) mitogen-activated protein kinase 3

Custom & Knockdown Gene Products

Antibodies

Product Number
Description
Species Reactivity
Application
Milli-Mark Anti-Phospho-Erk1/2 Antibody (Thr202/Tyr204, Thr185/Tyr187)-PE, clone AW39R, Milli-Mark®, from rabbit,
Species Reactivity
human, mouse, rat
Application
flow cytometry
western blot
Anti-phospho-MAPK 1/2 (Thr203/Ty205) Antibody, clone 14B9.1, clone 14B9.1, from mouse,
Species Reactivity
human
Application
western blot
Anti-ERK1/2 Antibody, clone 16A6.1, clone 16A6.1, from mouse,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-phospho-Erk1/2 (Thr202/Tyr204, Thr185/Tyr187)Antibody, recombinant clone AW39R, rabbit monoclonal, clone AW39R, Upstate®, from rabbit,
Species Reactivity
human, mouse, rat
Application
multiplexing
western blot

Proteins

Product Number
Description
Species
MAP Kinase 1/Erk1 Protein, active, 10 µg, Active, recombinant, full-length, human MAP Kinase 1/Erk1 containing an N-terminal GST tag, for use in Kinase Assays.,
Species
human