KRT8
keratin 8
Synonyms:
CARD2, CK-8, CK8, CYK8, K2C8, K8, KO
Species:
Human KRT8 (3856), Mouse Krt8 (16691), Rat Krt8 (25626), domestic guinea pig Krt8 (100736243), cow KRT8 (281269), Zebrafish krt8 (797433), domestic cat KRT8 (101081312), naked mole-rat Krt8 (101714648), Domestic Rabbit KRT8 (100348891), sheep KRT8 (101110495) ...More
UniProtKB ID:
Gene ID:
- Human(3856) Summary: This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
- Mouse(16691) keratin 8
- Rat(25626) keratin 8
- domestic guinea pig(100736243) keratin 8
- cow(281269) keratin 8
- Zebrafish(797433) keratin 8
- domestic cat(101081312) keratin 8
- naked mole-rat(101714648) keratin 8
- Domestic Rabbit(100348891) keratin 8
- sheep(101110495) keratin 8
- chicken(426896) keratin 8
- dog(486513) keratin 8
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Cytokeratin-8 Antibody, clone 1E8, ,
Species Reactivity
canine, human, monkey
Application
immunocytochemistry
immunohistochemistry
inhibition assay
western blot
immunohistochemistry
inhibition assay
western blot
Anti-phospho-KRT8 (pSer74) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
Monoclonal Anti-Cytokeratin Peptide 8 antibody produced in mouse, clone M20, ascites fluid,
Species Reactivity
bovine, canine, feline, human, rabbit
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-phospho-Keratin 8 (pSer432) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-Cytokeratin 8 Antibody, clone 4.1.18, clone 4.1.18, Chemicon®, from mouse,
Species Reactivity
human
Application
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot