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Merck

HTR5A

5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled

Synonyms:
5-HT5A
Species:
UniProtKB ID:
Gene ID:
  • Human(3361) Summary: The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. The gene described in this record is a member of 5-hydroxytryptamine (serotonin) receptor family and encodes a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G-proteins. This protein has been shown to function in part through the regulation of intracellular Ca2+ mobilization. [provided by RefSeq, Jul 2008]
  • Mouse(15563) 5-hydroxytryptamine (serotonin) receptor 5A
  • Rat(25689) 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
  • cow(541200) 5-hydroxytryptamine (serotonin) receptor 5A
  • Horse(100063709) 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
  • domestic cat(101084611) 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
  • Zebrafish(100038775) 5-hydroxytryptamine (serotonin) receptor 5A
  • dog(482814) 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
  • sheep(101116905) 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
  • naked mole-rat(101723065) 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
  • domestic guinea pig(100379278) 5-hydroxytryptamine (serotonin) receptor 5A
  • chicken(428409) 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled

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Small Molecule - Agonist

Product Number
Description
Species
5-Carboxamidotryptamine maleate salt, powder, ≥98% (HPLC),
Species
human, rat
(+)-Fenfluramine hydrochloride, ,
Species
human
Quipazine maleate salt, ,
Species
human

Small Molecule - Allosteric Modulator

Product Number
Description
Species
DCEBIO, ≥98% (HPLC), solid,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
5-Carboxamidotryptamine maleate salt, powder, ≥98% (HPLC),
Species
human, rat
Amisulpride, ≥98% (HPLC),
Species
human
Amisulpride, European Pharmacopoeia (EP) Reference Standard,
Species
human
Amisulpride, British Pharmacopoeia (BP) Reference Standard,
Species
human
Amisulpride for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-HTR5A (AB1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
Anti-HTR5A (AB2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, dog, guinea pig, horse, human, monkey, mouse, rat
Application
ELISA
immunohistochemistry
Anti-HTR5A antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
Anti-HTR5A antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot

Small Molecule - Blocker

Product Number
Description
Species
Trimipramine maleate salt, ≥98% (TLC), powder,
Species
human
Zimelidine dihydrochloride, solid,
Species
human

Small Molecule - Inhibitor

Product Number
Description
Species
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
Species
human
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
Species
human
Sertraline hydrochloride, ≥98% (HPLC),
Species
human
Fluvoxamine maleate, solid,
Species
human
Citalopram hydrobromide, ≥98% (HPLC),
Species
human

Small Molecule - Ligand

Product Number
Description
Species
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Species
human

Small Molecule - Metabolite

Product Number
Description
Species
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
Species
human

Small Molecule - Precursor

Product Number
Description
Species
5-Hydroxy-L-tryptophan, powder,
Species
human

Proteins

Product Number
Description
Species
ChemiSCREEN Membrane Preparation Recombinant Human 5-HT5A Serotonin Receptor, ,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human HTR5A,
Species
human