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Merck

FGF2

fibroblast growth factor 2 (basic)

Synonyms:
BFGF, FGF-2, FGFB, HBGF-2
Species:
UniProtKB ID:
Gene ID:
  • Human(2247) Summary: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. [provided by RefSeq, Jul 2008]
  • Mouse(14173) fibroblast growth factor 2
  • Rat(54250) fibroblast growth factor 2
  • Zebrafish(404231) fibroblast growth factor 2
  • chicken(396413) fibroblast growth factor 2 (basic)
  • domestic cat(100135772) fibroblast growth factor 2 (basic)
  • dog(403857) fibroblast growth factor 2 (basic)
  • cow(281161) fibroblast growth factor 2 (basic)
  • Horse(100033955) fibroblast growth factor 2 (basic)
  • Domestic Rabbit(100009068) fibroblast growth factor 2 (basic)
  • sheep(443306) fibroblast growth factor 2 (basic)
  • naked mole-rat(101720583) fibroblast growth factor 2 (basic)
  • domestic guinea pig(100721182) fibroblast growth factor 2 (basic)

Custom & Knockdown Gene Products

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-FGF-2/basic FGF Antibody, clone bFM-2, clone bFM-2, Upstate®, from mouse,
Species Reactivity
bovine, human, mouse, rat
Application
immunohistochemistry
radioimmunoassay

western blot
Anti-FGF-2/basic FGF (neutralizing) Antibody, clone bFM-1, clone bFM-1, Upstate®, from mouse,
Species Reactivity
bovine, human, mouse, rat
Application
neutralization
radioimmunoassay