DOCK8
dedicator of cytokinesis 8
Synonyms:
MRD2, ZIR8
Species:
Human DOCK8 (81704), Mouse Dock8 (76088), Rat Dock8 (499337), Domestic Rabbit DOCK8 (100354750), dog DOCK8 (476333), domestic cat DOCK8 (101101598), Horse DOCK8 (100050677), chicken DOCK8 (427348), Zebrafish dock8 (403040), domestic guinea pig Dock8 (100727594) ...More
UniProtKB ID:
Gene ID:
- Human(81704) Summary: This gene encodes a member of the DOCK180 family of guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with Rho GTPases and are components of intracellular signaling networks. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Jun 2010]
- Mouse(76088) dedicator of cytokinesis 8
- Rat(499337) dedicator of cytokinesis 8
- Domestic Rabbit(100354750) dedicator of cytokinesis 8
- dog(476333) dedicator of cytokinesis 8
- domestic cat(101101598) dedicator of cytokinesis 8
- Horse(100050677) dedicator of cytokinesis 8
- chicken(427348) dedicator of cytokinesis 8
- Zebrafish(403040) dedicator of cytokinesis 8
- domestic guinea pig(100727594) dedicator of cytokinesis 8
- naked mole-rat(101701061) dedicator of cytokinesis 8
- cow(100295817) dedicator of cytokinesis 8
- sheep(101116636) dedicator of cytokinesis 8
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