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Merck

CYP2C18

cytochrome P450, family 2, subfamily C, polypeptide 18

Synonyms:
CPCI, CYP2C, CYP2C17, P450-6B/29C, P450IIC17
Species:
UniProtKB ID:
Gene ID:
  • Human(1562) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum but its specific substrate has not yet been determined. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. An additional gene, CYP2C17, was once thought to exist; however, CYP2C17 is now considered an artefact based on a chimera of CYP2C18 and CYP2C19. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • cow(535243) cytochrome P450, family 2, subfamily C, polypeptide 18
  • chicken(414841) cytochrome P450, family 2, subfamily C, polypeptide 18
  • dog(415122) cytochrome P450 2C21
  • sheep(100568290) cytochrome P450 2C18

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Cyp2C18 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
Anti-CYP2C18 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Sulfaphenazole, ≥98%,
Species
human
Sulfaphenazole, ≥98% (HPLC),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CYP2C18,
Species
human