BCL2L1
BCL2-like 1
Synonyms:
BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS
Species:
Human BCL2L1 (598), Mouse Bcl2l1 (12048), Rat Bcl2l1 (24888), Domestic Rabbit BCL2L1 (100008875), domestic guinea pig Bcl2l1 (100730495), Zebrafish bcl2l1 (114401), cow BCL2L1 (282152), domestic cat BCL2L1 (493701), chicken BCL2L1 (373954), dog BCL2L1 (403618) ...More
UniProtKB ID:
Gene ID:
- Human(598) Summary: The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator. [provided by RefSeq, Jul 2008]
- Mouse(12048) BCL2-like 1
- Rat(24888) Bcl2-like 1
- Domestic Rabbit(100008875) BCL2-like 1
- domestic guinea pig(100730495) BCL2-like 1
- Zebrafish(114401) bcl2-like 1
- cow(282152) BCL2-like 1
- domestic cat(493701) BCL2-like 1
- chicken(373954) BCL2-like 1
- dog(403618) BCL2-like 1
- sheep(443061) BCL2-like 1
- naked mole-rat(101713410) BCL2-like 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-BCL2L1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
canine, human
Application
western blot
Anti-BCL2L1 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
bovine, dog, horse, human, pig, rabbit, sheep
Application
western blot
Anti-Bcl-XL Antibody, clone 2V10G9, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
western blot
Anti-Bcl-xL Antibody, clone 1O8 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
bovine, canine, feline, human, monkey, mouse, porcine, rat
Application
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-Bcl-X Antibody, clone 2H12, clone 2H12, Chemicon®, from mouse,
Species Reactivity
human, mouse, pig, rat
Application
flow cytometry
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
Proteins
Product Number
Description
Species