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Merck

ADORA1

adenosine A1 receptor

Synonyms:
RDC7
Species:
UniProtKB ID:
Gene ID:
  • Human(134) Summary: The protein encoded by this gene is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication. Transcript variants with alternative splicing in the 5' UTR have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(11539) adenosine A1 receptor
  • Rat(29290) adenosine A1 receptor
  • chicken(374212) adenosine A1 receptor
  • sheep(101109816) adenosine A1 receptor
  • cow(282133) adenosine A1 receptor
  • domestic guinea pig(100135472) adenosine A1 receptor
  • naked mole-rat(101704638) adenosine A1 receptor
  • Zebrafish(100150997) adenosine A1 receptor
  • dog(403961) adenosine A1 receptor
  • domestic cat(101100536) adenosine A1 receptor

Custom & Knockdown Gene Products

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  • Custom Gene Products

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Small Molecule - Agonist

Product Number
Description
Species
(−)-N6-(2-Phenylisopropyl)adenosine, solid,
Species
human
Formycin A, from Streptomyces kaniharaensis, ≥98% (HPLC),
Species
human
AB-MECA, solid,
Species
human, rat
Adenosine, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Adenosine, ,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
Tubercidin, from Streptomyces tubercidicus, ~95%,
Species
rat
8-Cyclopentyl-1,3-dimethylxanthine, ≥98% (HPLC), powder,
Species
human
Cordycepin, from Cordyceps militaris,
Species
rat
3-Methylxanthine, 98%,
Species
rat
9-Methyladenine, 97%,
Species
rat

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ADORA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-ADORA1 antibody produced in rabbit, ,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
Anti-ADORA1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, rat
Application
ELISA
western blot
Anti-Adenosine A1 Receptor Antibody, Chemicon®, from rabbit,
Species Reactivity
guinea pig, human, pig, rat, sheep
Application
ELISA
immunocytochemistry

immunohistochemistry

western blot
Anti-A1 Adenosine Receptor antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, human, rat
Application
immunohistochemistry
immunoprecipitation (IP)

western blot

Small Molecule - Blocker

Product Number
Description
Species
Caffeine, SAJ special grade, ≥98.5%,
Species
human
Nitrendipine, >95%, powder,
Species
human, rat
Caffeine, anhydrous, 99%, FCC, FG,
Species
mouse, human, rat
Caffeine, anhydrous, tested according to Ph. Eur.,
Species
mouse, human, rat
Caffeine, Sigma Reference Standard, vial of 250 mg,
Species
mouse, human, rat

Small Molecule - Inhibitor

Product Number
Description
Species
8-(3-Chlorostyryl)caffeine, ≥98% (HPLC), solid,
Species
human, rat, mouse
EHNA hydrochloride, ≥98% (HPLC),
Species
human
Dilazep dihydrochloride, powder,
Species
human
Galangin, autophagy inducing flavonoid,
Species
human, rat
5′-Deoxy-5′-(methylthio)adenosine, ,
Species
human, rat, mouse

Small Molecule - Ligand

Product Number
Description
Species
2-Chloro-2′-deoxyadenosine, antileukemic,
Species
rat, human
1,7-Dimethylxanthine, ~98%, solid,
Species
rat, human
Chloro-IB-MECA, solid, ≥98% (HPLC),
Species
human, rat
Adenosine, ≥99%,
Species
human, rat
Theophylline, anhydrous, ≥99%, powder,
Species
mouse, human, rat

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Adora1,
Species
mouse
MISSION® esiRNA, targeting human ADORA1,
Species
human