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Merck

47889

Supelco

Methyl Paraben

PESTANAL®, analytical standard

Sinónimos:

Metil 4-hidroxibenzoato, Éster metílico del ácido p-hidroxibenzoico, Metil parabeno, NIPAGIN

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About This Item

Fórmula lineal:
HOC6H4CO2CH3
Número de CAS:
Peso molecular:
152.15
Beilstein/REAXYS Number:
509801
EC Number:
MDL number:
UNSPSC Code:
12164500
PubChem Substance ID:
E Number:
E218

grade

analytical standard

product line

PESTANAL®

CofA

current certificate can be downloaded

packaging

ampule of 1000 mg

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

125-128 °C (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

storage temp.

2-30°C

SMILES string

COC(=O)c1ccc(O)cc1

InChI

1S/C8H8O3/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5,9H,1H3

InChI key

LXCFILQKKLGQFO-UHFFFAOYSA-N

Gene Information

rat ... Ar(24208)

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General description

Methyl Paraben is a stable, non-volatile, methyl ester of p-hydroxybenzoic acid. It can find applications as a broad-spectrum antimicrobial preservative in foods, drugs and cosmetics. It is found to be noncarcinogenic and is highly effective against fungi like molds and yeast as well as bacteria.
Methyl paraben is basically a methyl ester of p-hydroxybenzoic acid. It is non-toxic, and non-carcinogenic in nature. It is a stable, non-volatile compound and finds application as an anti-microbial preservative in foods, drugs and cosmetics. It is readily absorbed through the skin and gastrointestinal tract. Upon hydrolyzation, it is hydrolyzed to p-hydroxybenzoic acid, and the conjugates formed get rapidly excreted in the urine.

Application

Methyl paraben was used a preservative standard in commercial food products, during an experimental investigation, done to study the application of microemulsion electrokinetic chromatography (MEEKC), in detecting food preservatives.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Environment

hcodes

Hazard Classifications

Aquatic Chronic 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

334.4 °F

flash_point_c

168 °C

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Certificados de análisis (COA)

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Visite la Librería de documentos

Chul-Hong Kim et al.
Genes, 12(2) (2021-03-07)
Bisphenol A (BPA) is a xenoestrogen chemical commonly used to manufacture polycarbonate plastics and epoxy resin and might affect various human organs. However, the cellular effects of BPA on the eyes have not been widely investigated. This study aimed to
Evaluation of the health aspects of methyl paraben: a review of the published literature
Soni.G.M, et al.
Food And Chemical Toxicology, 40, 1335-1373 (2002)
Evaluation of the health aspects of methyl paraben: a review of the published literature.
Soni MG
Food And Chemical Toxicology, 40 (10), 1335-1373 (2002)
Combined activation of methyl paraben by light irradiation and esterase metabolism toward oxidative DNA damage
Okamoto Y, et al.
Chemical Research in Toxicology, 21, 1594-1599 (2008)
Application of microemulsion electrokinetic chromatography for the detection of preservatives in foods.
Huang H.y
Food Chemistry, 89 (2), 315-322 (2005)

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