Saltar al contenido
Merck
Todas las fotos(1)

Key Documents

View All Documentation

T0397

Sigma-Aldrich

L-Thyroxine sodium salt pentahydrate

γ-irradiated, powder, BioXtra, suitable for cell culture

Sinónimos:

3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-L-alanine sodium salt, Sodium levothyroxine, T4

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(1)

About This Item

Fórmula lineal:
HOC6H2I2OC6H2I2CH2CH(NH2)COONa · 5H2O
Número de CAS:
6106-07-6
Peso molecular:
888.93
Beilstein/REAXYS Number:
5721845
EC Number:
200-221-4
MDL number:
MFCD00149110
UNSPSC Code:
12352209
PubChem Substance ID:
24899887
NACRES:
NA.77

biological source

synthetic (organic)

Quality Level

200

sterility

γ-irradiated

product line

BioXtra

assay

≥98%

form

powder

potency

5-50 ng/mL

technique(s)

cell culture | mammalian: suitable

mp

207-210 (dec.) (lit.)

solubility

cell culture medium: 0.1 mg/mL
H2O: soluble

storage temp.

−20°C

SMILES string

O.O.O.O.O.[Na+].N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C([O-])=O

InChI

1S/C15H11I4NO4.Na.5H2O/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;;;;;;/h1-2,4-5,12,21H,3,20H2,(H,22,23);;5*1H2/q;+1;;;;;/p-1/t12-;;;;;;/m0....../s1

InChI key

JMHCCAYJTTWMCX-QWPJCUCISA-M

Gene Information

mouse ... Cnr2(12802)
rat ... Cnr1(25248)

¿Está buscando productos similares? Visita Guía de comparación de productos

Categorías relacionadas

Biochem/physiol Actions

L-Thyroxine (T4) and triiodo-L-thyronine (T3) are iodine-containing hormones produced from thyroglobulin in the thyroid follicular cells. The stimulation of metabolic rate and regulation of growth and development by these hormones appear to be due to their effects on DNA transcription and thus, protein synthesis.

Physical form

powder-0 °C; stock-frozen in working aliquots, avoid repeated freeze/thaw, solution stable 2-8 °C, 30 days

Reconstitution

To prepare 20 μg/ml stock solution, add 50 ml sterile culture medium.

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H372

Hazard Classifications

STOT RE 1

target_organs

Thyroid,Cardio-vascular system,Kidney

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Giuseppe Ianiri et al.
mBio, 6(2) (2015-04-02)
Fungal diseases represent a major burden to health care globally. As with other pathogenic microbes, there is a limited number of agents suitable for use in treating fungal diseases, and resistance to these agents can develop rapidly. Cryptococcus neoformans is
Mahdokht Jouiaei et al.
Molecular biology and evolution, 32(6), 1598-1610 (2015-03-12)
Despite Cnidaria (sea anemones, corals, jellyfish, and hydroids) being the oldest venomous animal lineage, structure-function relationships, phyletic distributions, and the molecular evolutionary regimes of toxins encoded by these intriguing animals are poorly understood. Hence, we have comprehensively elucidated the phylogenetic
Lilian Pukk et al.
Molecular ecology resources, 15(5), 1145-1152 (2015-02-24)
Massively parallel sequencing a small proportion of the whole genome at high coverage enables answering a wide range of questions from molecular evolution and evolutionary biology to animal and plant breeding and forensics. In this study, we describe the development
Laam Li et al.
BMC genomics, 16, 637-637 (2015-08-27)
Legionella pneumophila (Lp) is a water-borne opportunistic pathogen. In water, Lp can survive for an extended period of time until it encounters a permissive host. Therefore, identifying genes that are required for survival in water may help develop strategies to
Naoomi Tominaga et al.
Nature communications, 6, 6716-6716 (2015-04-02)
Brain metastasis is an important cause of mortality in breast cancer patients. A key event during brain metastasis is the migration of cancer cells through blood-brain barrier (BBB). However, the molecular mechanism behind the passage through this natural barrier remains
Ver todos los artículos relacionados

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico