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P6501

Sigma-Aldrich

Phenyl-β-D-galactopyranoside

≥98% (TLC)

Sinónimos:

P-Gal, Phenyl β-D-galactoside

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About This Item

Fórmula empírica (notación de Hill):
C12H16O6
Número de CAS:
2818-58-8
Peso molecular:
256.25
Beilstein/REAXYS Number:
87518
EC Number:
220-573-2
MDL number:
MFCD00063258
UNSPSC Code:
41141627
PubChem Substance ID:
24898771
NACRES:
NA.52

grade

for mineral oil production sites, untaxed

assay

≥98% (TLC)

form

powder

storage temp.

−20°C

SMILES string

OC[C@H]1O[C@@H](Oc2ccccc2)[C@H](O)[C@@H](O)[C@H]1O

InChI

1S/C12H16O6/c13-6-8-9(14)10(15)11(16)12(18-8)17-7-4-2-1-3-5-7/h1-5,8-16H,6H2/t8-,9+,10+,11-,12-/m1/s1

InChI key

NEZJDVYDSZTRFS-YBXAARCKSA-N

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General description

Phenyl-β-D-galactopyranoside is used as a substrate for detecting β-galactosidase enzymatic activity.

Application

Phenyl-β-D-galactopyranoside has been used in mutant phage screening.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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M Ring et al.
Biochemical and biophysical research communications, 131(2), 675-680 (1985-09-16)
The pH profiles of beta-galactosidase, having tyr replaced by m-fluorotyrosine, were compared to those of normal enzyme. The inflection point on the alkaline side was lowered about 1.5 pH units in the fluoro-enzyme, corresponding to the difference in the phenolic
J Jiao et al.
Mutation research, 372(1), 141-145 (1996-11-11)
lacZ gene mutations in the transgenic Muta Mmouse can be detected by two different selection systems. While mutant frequencies recovered by phenyl-beta-D-galactoside (P-gal) selection are comparable with those obtained using 5-bromo-4-chloro-3-indolyl beta-D-galactopyranoside (X-gal) as substrate for beta-galactosidase, there may still
Ziyu Deng et al.
International journal of biological macromolecules, 137, 69-76 (2019-07-02)
β-Galactosidase (β-Gal) as dietary supplement has the ability to alleviate symptoms of lactose intolerance. This study investigated the ability of oligosaccharides to protect β-Gal against heat stress. Four kinds of oligosaccharides including Isomalto-oligosaccharides (IMO), Xylo-oligosaccharides (XOS), Konjac-oligosaccharides (KOS), and Mycose
Zbynek Oktabec et al.
Molecules (Basel, Switzerland), 15(12), 8973-8987 (2010-12-15)
Mixtures of ibandronate monosodium salt with eleven gluco- and/or galacto-pyranoside derivatives as counterions were designed to prepare co-crystals with improved intestinal absorption. In general, gastrointestinal absorption of bisphosphonates after oral administration is approximately 1%. Co-crystals were generated by means of
Daniel D Mitchell et al.
Bioorganic & medicinal chemistry, 12(5), 907-920 (2004-02-26)
With the aim of developing high-affinity mono and multivalent antagonists of cholera toxin (CT) and Escherichia coli heat-labile enterotoxin (LT) we are using the galactose portion of the natural receptor ganglioside GM1 as an anchoring fragment in structure-based inhibitor design
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