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Merck
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Documentos clave

318A-1

Sigma-Aldrich

PGP 9.5 Rabbit Polyclonal Antibody

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

100
500

conjugado

unconjugated

forma del anticuerpo

Ig fraction of antiserum

tipo de anticuerpo

primary antibodies

clon

polyclonal

descripción

For In Vitro Diagnostic Use in Select Regions (See Chart)

Formulario

buffered aqueous solution

reactividad de especies

human

envase

vial of 0.1 mL concentrate (318A-14)
vial of 0.5 mL concentrate (318A-15)
bottle of 1.0 mL predilute (318A-17)
vial of 1.0 mL concentrate (318A-16)
bottle of 7.0 mL predilute (318A-18)

fabricante / nombre comercial

Cell Marque®

técnicas

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

control

nerve tissue

Condiciones de envío

wet ice

temp. de almacenamiento

2-8°C

visualización

cytoplasmic

Categorías relacionadas

Descripción general

Protein gene product 9.5 (PGP 9.5), also known as ubiquitin carboxyl-terminal hydrolase-1 (UCHL-1), is a 27 kDa protein originally isolated from whole brain extracts. Although PGP 9.5 expression in normal tissues was originally felt to be strictly confined to neurons and neuroendocrine cells, it has been subsequently documented in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. A plethora of mesenchymal neoplasms have demonstrated PGP 9.5 expression.

Calidad


IVD
IVD
IVD
RUO

Ligadura / enlace

PGP9.5 Positive Control Slides, Product No. 318S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota de preparación

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Otras notas

For Technical Service please contact: 800-665-7284 or email: [email protected]

Información legal

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Certificados de análisis (COA)

Lot/Batch Number
0000415867
0000415868
0000415870
0000415868
0000415867

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Lucas K Campbell et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 16(10), 963-969 (2003-10-16)
In non-neoplastic tissues, the expression of protein gene product 9.5 (PGP 9.5), a member of the ubiquitin hydrolase family of proteins, is confined to neural and neuroendocrine cells. Although it has been claimed that PGP 9.5 is a specific marker
G Bassotti et al.
Journal of clinical pathology, 58(9), 973-977 (2005-08-30)
Colonic diverticular disease (diverticulosis) is a common disorder in Western countries. Although its pathogenesis is probably multifactorial, motor abnormalities of the large bowel are thought to play an important role. However, little is known about the basic mechanism that may
M Mahalingam et al.
Journal of cutaneous pathology, 28(6), 282-286 (2001-06-13)
Protein gene product 9.5 (PGP 9.5) is expressed in brain at 20 to 50 times the levels detected in other organs. Immunohistochemical studies reveal this protein is localized to both central and peripheral neurons. Recently, PGP 9.5 is reported to
M Mahalingam et al.
Journal of cutaneous pathology, 33(1), 51-56 (2006-01-31)
Cellular neurothekeoma is a relatively rare, benign cutaneous neoplasm, which usually presents as a solitary papule or nodule involving the head and neck area of young adults. Multiple neurothekeomas have not, to date, been known to occur. We report a

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