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145M-9

Sigma-Aldrich

CD45 (LCA) (2B11 & PD7/26) Mouse Monoclonal Antibody

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

origen biológico

mouse

Nivel de calidad

100
500

conjugado

unconjugated

forma del anticuerpo

culture supernatant

tipo de anticuerpo

primary antibodies

clon

2B11 & PD7/26, monoclonal

descripción

For In Vitro Diagnostic Use in Select Regions (See Chart)

Formulario

buffered aqueous solution

reactividad de especies

human

envase

vial of 0.1 mL concentrate (145M-94)
vial of 0.5 mL concentrate (145M-95)
bottle of 1.0 mL predilute (145M-97)
vial of 1.0 mL concentrate (145M-96)
bottle of 7.0 mL predilute (145M-98)

fabricante / nombre comercial

Cell Marque®

técnicas

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

isotipo

IgG1κ

control

tonsil

Condiciones de envío

wet ice

temp. de almacenamiento

2-8°C

visualización

membranous

Información sobre el gen

human ... PTPRC(5788)

Categorías relacionadas

Descripción general

Anti-CD45 (anti-leukocyte common antigen) is routinely used to aid the differential diagnosis of undifferentiated neoplasms, whenever malignant lymphoma is suspected by the morphological or clinical data. It is a highly specific antibody; therefore a positive result is highly indicative of hematolymphoid origin. Certain types of hematolymphoid neoplasms may lack CD45 (Hodgkin lymphoma, some T-cell lymphomas, and some leukemias) its absence does not rule out a hematolymphoid tumor. This antibody is expressed almost exclusively by cells of the hematopoietic lineage and is present in most benign and malignantlymphocytes as well as plasma cell precursors.

Calidad


IVD
IVD
IVD
RUO

Ligadura / enlace

CD45 (LCA) Positive Control Slides, Product No. 145S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota de preparación

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Otras notas

For Technical Service please contact: 800-665-7284 or email: [email protected]

Información legal

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Certificados de análisis (COA)

Lot/Batch Number
0000394797
0000394797
0000404859
0000392569
0000384718

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T Caballero et al.
Journal of clinical pathology, 48(8), 743-748 (1995-08-01)
To gain new insights into the pathogenesis and differential diagnosis of ulcerative colitis and colonic Crohn's disease. Immunohistochemistry for different leucocyte subsets was performed in biopsy specimens of the sigmoid colon and rectum from 55 patients with inflammatory bowel disease
A Saxena et al.
American journal of clinical pathology, 112(4), 495-512 (1999-10-08)
In the multiparametric evaluation of cutaneous B-cell infiltrates (CBIs), immunoarchitectural features have been underused, and B-cell clonality alone has limited clinical usefulness. Our aim was to assess the usefulness of immunoarchitectural abnormalities (IAs) and clonality in the diagnosis of CBIs.
M A Vasef et al.
American journal of clinical pathology, 108(1), 54-59 (1997-07-01)
Other studies have shown that the immunophenotype of Reed-Sternberg and Hodgkin's (RS-H) cells in Hodgkin's disease commonly changes over time, as shown by examination of multiple biopsy specimens obtained from an individual patient. In this study we analyzed 96 sequential
H M Maluf et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 8(2), 155-159 (1995-02-01)
Giant cell tumor of tendon sheath (GCTTS; "nodular tenosynovitis") and fibroma of tendon sheath (FTS) have traditionally been considered to be two points in a single neoplastic continuum. However, no systematic studies have addressed this concept directly to date. To
P J Kurtin et al.
Human pathology, 16(4), 353-365 (1985-04-01)
Immunohistochemical localization of human leukocyte common antigen (LCA), a major membrane glycoprotein restricted to leukocytes, was evaluated in paraffin sections of a wide variety of hematopoietic and nonhematopoietic tissues (294 specimens) with monoclonal antibodies (PD7/26 and 2B11). In nonneoplastic tissues
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