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Key Documents

PHR1904

Supelco

Citalopram Related Compound E

Pharmaceutical Secondary Standard; Certified Reference Material

Sinónimos:

1-(3-Dimethylaminopropyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile N-oxide hydrochloride, 1-(3-DIMETHYLAMINOPROPYL)-1-(4-FLUOROPHENYL)-1,3-DIHYDROISOBENZOFURAN-5-CARBONITRILE-N-OXIDE HYDROCHLORIDE

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About This Item

Fórmula empírica (notación de Hill):
C20H21FN2O2 · HCl
Peso molecular:
376.85
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

agency

traceable to USP 1134288

API family

citalopram

CofA

current certificate can be downloaded

packaging

pkg of 50 mg

application(s)

pharmaceutical small molecule

format

neat

storage temp.

2-30°C

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General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Citalopram Related Compound E is a related impurity found in the drug Citalopram. Citalopram is a racemic bicyclic phthalane derivative and is a potent anti-depressant drug, that acts by inhibition of serotonin uptake.

Application

Citalopram Related Compound E may be used as a pharmaceutical reference standard for the determination of the analyte in bulk drug and pharmaceutical formulations by chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAB1229 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

related product

Referencia del producto
Descripción
Precios

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Certificados de análisis (COA)

Lot/Batch Number

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Visite la Librería de documentos

Citalopram Hydrobromide
USP42/NF37
United States Pharmacopeia/National Formulary, 39(6), 1018-1018 (2018)
Semi-preparative isolation and structural elucidation of an impurity in citalopram by LC/MS/MS
Raman B, et al.
Journal of Pharmaceutical and Biomedical Analysis, 50(3), 377-383 (2009)

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