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Merck

45339

Supelco

Benomyl

PESTANAL®, analytical standard

Sinónimos:

Methyl 1-(butylcarbamoyl)-2-benzimidazolecarbamate

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About This Item

Fórmula empírica (notación de Hill):
C14H18N4O3
Número de CAS:
Peso molecular:
290.32
Beilstein/REAXYS Number:
825455
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

>300 °C (lit.)

application(s)

agriculture
cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

storage temp.

2-8°C

SMILES string

CCCCNC(=O)n1c(NC(=O)OC)nc2ccccc12

InChI

1S/C14H18N4O3/c1-3-4-9-15-13(19)18-11-8-6-5-7-10(11)16-12(18)17-14(20)21-2/h5-8H,3-4,9H2,1-2H3,(H,15,19)(H,16,17,20)

InChI key

RIOXQFHNBCKOKP-UHFFFAOYSA-N

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General description

Benomyl is characterized under the benzimidazole fungicide and is known to suppress fungal growth in a wide variety of plants. Its mode of action involves inhibition of tubulin polymerization.

Application

Benomyl may be used as a reference standard for the determination of benomyl in aqueous media by high-performance liquid chromatographic method.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Muta. 1B - Repr. 1B - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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Certificados de análisis (COA)

Lot/Batch Number

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Visite la Librería de documentos

High-performance liquid chromatographic method for simultaneous determination of benomyl and carbendazim in aqueous media.
Chiba M, et al.
Journal of Agricultural and Food Chemistry, 34(1), 108-112 (1986)
Miriam Böhm et al.
eLife, 10 (2021-07-27)
Kinetochores are multi-subunit protein assemblies that link chromosomes to microtubules of the mitotic and meiotic spindle. It is still poorly understood how efficient, centromere-dependent kinetochore assembly is accomplished from hundreds of individual protein building blocks in a cell cycle-dependent manner.
Deleterious effects of benomyl and carbendazim on human placental trophoblast cells.
Zhou J, et al.
Reproductive Toxicology, 51, 64-71 (2015)
Teratogenic effects of benomyl in the Wistar rat and CD-1 mouse, with emphasis on the route of administration.
Kavlock RJ, et al.
Toxicology and Applied Pharmacology, 62(1), 44-54 (1982)
Babhrubahan Roy et al.
eLife, 9 (2020-06-02)
During mitosis, the Spindle Assembly Checkpoint (SAC) maintains genome stability while also ensuring timely anaphase onset. To maintain genome stability, the SAC must be strong to delay anaphase even if just one chromosome is unattached, but for timely anaphase onset

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