1.51908

LiChrospher^® 100 RP-18 endcapped (5 µm) HPLC Columns

L x I.D. 125 mm x 4 mm LiChroCART^™ HPLC cartridge, manuCART^™ holder required for use

• Sinónimos: TM=["LiChrospher"] C18 TM=["LICHROCART"] cartridge for HPLC
• UNSPSC Code: 41115700
• NACRES: SB.52

Propiedades

• product name: LiChrospher^® 100 RP-18 endcapped (5µm) LiChroCART^™ 125-4.6, suitable for HPLC
• material: stainless steel column
• agency: suitable for USP L1
• product line: LiChrospher^®
• feature: endcapped
• packaging: 1 ea of
• extent of labeling: 21.6% Carbon loading
• parameter: 250 bar pressure; 60 °C max. temp.
• technique(s): HPLC: suitable; mass spectrometry (MS): suitable (Low - Medium)
• column L × I.D.: 12.5 cm × 4.6 mm
• surface area: 350 m²/g
• matrix: fully porous particle
• matrix active group: C18 bonding phase
• particle size: 5 μm
• pore size: 100 Å pore size
• operating pH range: 2-7.5
• separation technique: reversed phase
• storage temp.: no temp limit

Descripción

General description

HPLC cartridge

Application

• Liquid chromatographic determination of lumacaftor in the presence of ivacaftor and identification of five novel degradation products using high-performance liquid chromatography ion trap time-of-flight mass spectrometry: This study effectively utilizes the Ascentis^® Express F5, 2.7 μm HPLC column to analyze complex pharmaceutical mixtures and identify degradation products, demonstrating the column′s high-resolution capabilities and robust performance in pharmaceutical analysis (Özcan et al., 2023).


• Stability-indicating LC-MS/MS and LC-DAD methods for robust determination of tasimelteon and high resolution mass spectrometric identification of a novel degradation product: This research highlights the use of the Ascentis^® Express F5 HPLC column in developing stability-indicating methods for the analysis of tasimelteon, underscoring its crucial role in ensuring the quality and safety of pharmaceuticals through advanced analytical techniques (Özcan et al., 2020).

Legal Information

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany

LICHROCART is a trademark of Merck KGaA, Darmstadt, Germany

LiChrospher is a registered trademark of Merck KGaA, Darmstadt, Germany