15502

1-Boc-piperazine

≥98.0% (GC)

• Sinónimos: tert-Butyl piperazine-1-carboxylate
• Fórmula empírica (notación de Hill): C₉H₁₈N₂O₂
• Número de CAS: 57260-71-6
• Peso molecular: 186.25
• Beilstein/REAXYS Number: 879985
• MDL number: MFCD00075265
• UNSPSC Code: 12352100
• eCl@ss: 32160406
• PubChem Substance ID: 57647377
• NACRES: NA.22

Propiedades

• Quality Level: 200
• assay: ≥98.0% (GC)
• form: solid
• mp: 43-47 °C (lit.); 43-47 °C
• SMILES string: CC(C)(C)OC(=O)N1CCNCC1
• InChI: 1S/C9H18N2O2/c1-9(2,3)13-8(12)11-6-4-10-5-7-11/h10H,4-7H2,1-3H3
• InChI key: CWXPZXBSDSIRCS-UHFFFAOYSA-N

Descripción

Application

1-Boc-piperazine undergoes Buchwald-Hartwig amination with various aryl halides to form corresponding amine derivatives. It can be used to synthesize monosubstituted piperazine intermediates of many bioactive molecules and piperazine containing drug substances, such as trazodone.

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: 235.4 °F - closed cup
• flash_point_c: 113 °C - closed cup
• ppe: dust mask type N95 (US), Eyeshields, Gloves