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A case of erythema multiforme developing after levetiracetam therapy.

Dermatology online journal (2013-03-12)
Yavuz Yesilova, Enver Turan, Abdurahman Sonmez, Ilyas Ozardali
ABSTRACT

Erythema multiforme is a skin disease, which occurs particularly in the acral region, and is characterized by target-like erythematous macules and papules. Infections play an important role in the etiology of erythema multiforme. Other causes include drugs, vaccination, and hematological malignancies. Half of all cases may not have an identifiable etiology. This article presents a male patient who developed erythema multiforme as a result of levetiracetam use for epilepsy.

MATERIALS
Product Number
Brand
Product Description

Levetiracetam impurity D, European Pharmacopoeia (EP) Reference Standard
Sigma-Aldrich
Piracetam
Levetiracetam, European Pharmacopoeia (EP) Reference Standard
Supelco
Levetiracetam solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
Sigma-Aldrich
Levetiracetam, ≥98% (HPLC)