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A0966

Sigma-Aldrich

4-Amino-1,8-naphthalimide

solid

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About This Item

Empirical Formula (Hill Notation):
C12H8N2O2
CAS Number:
1742-95-6
Molecular Weight:
212.20
EC Number:
217-110-1
MDL number:
MFCD00006921
UNSPSC Code:
12352204
PubChem Substance ID:
24277696
NACRES:
NA.83

product name

4-Amino-1,8-naphthalimide,

form

solid

mp

360 °C

density

1.105 g/mL at 25 °C (lit.)

storage temp.

−20°C

SMILES string

Nc1ccc2C(=O)NC(=O)c3cccc1c23

InChI

1S/C12H8N2O2/c13-9-5-4-8-10-6(9)2-1-3-7(10)11(15)14-12(8)16/h1-5H,13H2,(H,14,15,16)

InChI key

SSMIFVHARFVINF-UHFFFAOYSA-N

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Biochem/physiol Actions

4-Amino-1,8-naphthalimide sensitizes cells to radiation-induced cell damage and enhances the cytotoxicity of 1-methyl-3-nitro-1-nitrosoguanidine.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Organic letters, 13(5), 1190-1193 (2011-02-09)
A naphthalimide-based highly selective colorimetric and ratiometric fluorescent probe for the fluoride ion displayed both one- and two-photon ratiometric changes. Upon reaction with the F(-) (TBA(+) and Na(+) salts) anion in CH(3)CN as well as in aqueous buffer solution, probe
Marco A Alcala et al.
Nanomedicine : nanotechnology, biology, and medicine, 7(3), 249-258 (2010-10-16)
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Emma B Veale et al.
The Journal of organic chemistry, 75(16), 5513-5525 (2010-08-14)
The synthesis and characterization of three bis-1,8-naphthalimide-containing Tröger's bases 1-3, formed from the corresponding 4-amino-1,8-naphthalimide precursors 7-9 in a single step, is described. The photophysical investigation of 1-3 and 7-9 was carried out in various organic solvents as well as
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