60399

Potassium iodide

BioUltra, ≥99.5% (AT)

• Synonym(s): KI
• Linear Formula: KI
• CAS Number: 7681-11-0
• Molecular Weight: 166.00
• EC Number: 231-659-4
• MDL number: MFCD00011405
• UNSPSC Code: 12352302
• PubChem Substance ID: 57651758
• NACRES: NA.25

Properties

• vapor pressure: 1 mmHg ( 745 °C)
• product line: BioUltra
• Assay: ≥99.5% (AT)
• form: solid
• impurities: insoluble matter, passes filter test; ≤0.001% total nitrogen (N)
• loss: ≤0.5% loss on drying, 110 °C
• pH: 6.0-9.0 (25 °C, 1 M in H₂O)
• mp: 681 °C (lit.)
• solubility: H₂O: 1 M at 20 °C, clear, colorless
• anion traces: bromide, chloride (as Cl^-): ≤100 mg/kg; iodate (IO₃^-): ≤2 mg/kg; phosphate (PO₄^3-): ≤10 mg/kg; sulfate (SO₄^2-): ≤10 mg/kg
• cation traces: Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; Na: ≤300 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• absorption: cut-off at 273 nm in H₂O at 1 M
• application(s): vitamins, nutraceuticals, and natural products
• SMILES string: [K+].[I-]
• InChI: 1S/HI.K/h1H;/q;+1/p-1
• InChI key: NLKNQRATVPKPDG-UHFFFAOYSA-M

Description

Application

Potassium iodide has been used:

• to inhibit active oxygen as a component of processes such as DNA damage
• as a chaotropic agent which, in high concentrations can dissolve a gel matrix
• in the recovery of DNA from gel slices by gel dissolution

Biochem/physiol Actions

Potassium iodide (KI) consists of halogen iodine and the alkali metal potassium. It is used in the form of iodized salt to treat endemic goiter. KI is also used to treat hyperthyroidism and radiation protection of the thyroid gland. KI is useful for the preoperative preparation of patients with Grave′s disease. It also finds its use in treating dermatological conditions like cutaneous sporotrichosis and various inflammatory dermatoses. KI is commonly used as an expectorant. It inhibits the capacity of neutrophils to produce e toxic oxygen intermediates hydrogen peroxide and hydroxyl radicals in vitro.

Safety Information

• Pictograms: GHS08
• Signal Word: Danger
• Hazard Statements: H372
• Precautionary Statements: P260 - P264 - P270 - P314 - P501
• Hazard Classifications: STOT RE 1 Oral
• Target Organs: Thyroid
• Storage Class Code: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves