Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

203806

Millipore

5-Bromo-2′-deoxyuridine

Thymidine analog. Useful for the study of DNA synthesis where it is incorporated into DNA in place of thymidine.

Synonym(s):

5-Bromo-2′-deoxyuridine, 5-BrdU

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

CAS Number:
59-14-3
MDL number:
MFCD00006529
UNSPSC Code:
12352208
NACRES:
NA.51

Quality Level

100

Assay

≥98% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white

solubility

water: 10 mg/mL
0.1 M NaOH: 50 mg/mL
DMSO: 50 mg/mL

shipped in

ambient

storage temp.

15-25°C

InChI

1S/C9H11BrN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)

InChI key

WOVKYSAHUYNSMH-UHFFFAOYSA-N

General description

Thymidine analog. Used for the study of DNA synthesis where it is incorporated into DNA in place of thymidine. Can be used both in vitro and in vivo to label DNA. The resulting DNA can be used in conjuction with BrdU (Ab-2) Monoclonal Antibody (Cat. No. NA20) or BrdU Immunohistochemical System (Cat. No. HCS24) for the immunohistochemical analysis of cell proliferation.
Thymidine analog. Useful for the study of DNA synthesis where it is incorporated into DNA in place of thymidine. Can be used both in vitro and in vivo to label DNA. The resulting DNA can be used in conjunction with BrdU (Ab-2) Monoclonal Antibody (Cat. No. NA20) for the immunohistochemical analysis of cell proliferation.

Warning

Toxicity: Harmful & Carcinogenic / Teratogenic (E)

Reconstitution

Following reconstitution, sterilize by filtration through a 0.22 µm filter, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Garabedian, E.M., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 15382.
Cattoretti, G., et al. 1993. J. Pathol. 171, 83.
Fukuda, K., et al. 1990. Anal. Quant. Cytol. Histol. 12, 135.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H340,H361fd

Hazard Classifications

Muta. 1B - Repr. 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

J L Lubischer et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 19(20), 8931-8944 (1999-10-12)
Mature motoneurons respond to partial denervation of their target muscle by sprouting to reinnervate denervated fibers, thus maintaining muscle strength in the face of motoneuronal loss caused by injury or disease. Neonatal motoneurons, however, do not expand to innervate more
Tao Wei et al.
mBio, 12(4), e0227721-e0227721 (2021-09-02)
The species specificity of papillomaviruses has been a significant roadblock for performing in vivo pathogenesis studies in common model organisms. The Mus musculus papillomavirus type 1 (MmuPV1) causes cutaneous papillomas that can progress to squamous cell carcinomas in laboratory mice.
ShengPeng Wang et al.
Nature communications, 11(1), 2303-2303 (2020-05-10)
White adipose tissue (WAT) expansion in obesity occurs through enlargement of preexisting adipocytes (hypertrophy) and through formation of new adipocytes (adipogenesis). Adipogenesis results in WAT hyperplasia, smaller adipocytes and a metabolically more favourable form of obesity. How obesogenic WAT hyperplasia
Cristina Morales Torres et al.
Nature communications, 11(1), 1792-1792 (2020-04-15)
Continuous cancer growth is driven by subsets of self-renewing malignant cells. Targeting of uncontrolled self-renewal through inhibition of stem cell-related signaling pathways has proven challenging. Here, we show that cancer cells can be selectively deprived of self-renewal ability by interfering

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service