Skip to Content
Merck
All Photos(2)

Key Documents

View All Documentation

857133P

Avanti

18:1 BMP (S,R)

bis(monooleoylglycero)phosphate (S,R Isomer) (ammonium salt), powder

Synonym(s):

sn-(3--(9Z-octadecenoyl)-2-hydroxy)-glycerol-1-phospho-sn-3′-(1′--(9Z-octadecenoyl)-2′-hydroxy)-glycerol (ammonium salt); lysobisphosphatidic acid; LBPA; 110729

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C42H82NO10P
CAS Number:
326495-20-9
Molecular Weight:
792.07
UNSPSC Code:
51191904
NACRES:
NA.25

Assay

>99% (BMP (contains 30% positional isomers), TLC)

form

powder

packaging

pkg of 1 × 5 mg (857133P-5mg)
pkg of 1 × 50 mg (857133P-50mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 857133P

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP(OC[C@@]([H])(O)COC(CCCCCCC/C=C\CCCCCCCC)=O)([O-])=O)(O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+]

General description

18:1 BMP (S,R)/bis(monoacylglycero)phosphate (BMP) is also referred as lysobisphosphatidic acid. It is located to the membranes of endosomal origin.

Application

18:1 BMP (S,R) is suitable for use in the preparation of lipid vesicles.

Biochem/physiol Actions

18:1 BMP (S,R)/Lysobisphosphatidic acid (LBPA) can modulate endosomal cholesterol levels. It participates in cholesterol transport. LBPA helps to regulate the cholesterol storage capacity of endosomes.

Packaging

5 mL Clear Glass Sealed Ampule (857133P-50mg)
5 mL Clear Glass Sealed Ampule (857133P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Lysobisphosphatidic acid controls endosomal cholesterol levels
Chevallier J, et al.
The Journal of Biological Chemistry, 283(41), 27871-27880 (2008)
Elena Zaitseva et al.
PLoS pathogens, 6(10), e1001131-e1001131 (2010-10-16)
Many enveloped viruses invade cells via endocytosis and use different environmental factors as triggers for virus-endosome fusion that delivers viral genome into cytosol. Intriguingly, dengue virus (DEN), the most prevalent mosquito-borne virus that infects up to 100 million people each
Sophia C Goodchild et al.
PloS one, 9(8), e104492-e104492 (2014-08-08)
Although the molecular mechanisms underlying the pathology of amyloidoses are not well understood, the interaction between amyloid proteins and cell membranes is thought to play a role in several amyloid diseases. Amyloid fibrils of β2-microglobulin (β2m), associated with dialysis-related amyloidosis

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service