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Key Documents

675636

Sigma-Aldrich

Cupferron

97%, reagent grade

Synonym(s):

N-Nitroso-N-phenylhydroxylamine ammonium salt

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About This Item

Linear Formula:
C6H5N(NO)ONH4
CAS Number:
Molecular Weight:
155.15
Beilstein:
3919107
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.21

grade

reagent grade

Assay

97%

form

solid

technique(s)

titration: suitable

mp

150-155 °C (dec.) (lit.)

shipped in

wet ice

storage temp.

2-8°C

SMILES string

[H][N+]([H])([H])[H].[O-]N(N=O)c1ccccc1

InChI

1S/C6H5N2O2.H3N/c9-7-8(10)6-4-2-1-3-5-6;/h1-5H;1H3/q-1;/p+1

InChI key

GDEBSAWXIHEMNF-UHFFFAOYSA-O

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General description

Cupferron (Cup) is an ammonium salt of N-nitroso-N-phenylhydroxylamine. It acts as an organic chelation reagent by co-ordinating through the oxygen atoms. Its radiomimetic effect is reported to be affected by the pH and temperature of the treatment solution.

Application


  • A solvothermal route to ZnO and Mn-doped ZnO nanoparticles using the cupferron complex as the precursor.: This research presents a novel method to produce zinc oxide and manganese-doped zinc oxide nanoparticles using cupferron as a precursor, showcasing its application in material synthesis in analytical chemistry (Ghosh et al., 2004).

  • Determination of tellurium in geochemical materials by flameless atomic-absorption spectroscopy.: Demonstrates the role of cupferron in enhancing the analytical methodologies for tellurium determination, underpinning its significance in geochemical studies (Sighinolfi et al., 1979).

  • Extraction of vanadium into isobutyl methyl ketone.: Outlines a method for extracting vanadium using cupferron, which plays a crucial role in the development of methods for the quantitative analysis of vanadium in various samples (Crump-Wiesner and Purdy, 1969).

  • Substituted hydroxylamines as analytical reagents.: Discusses the application of substituted hydroxylamines, including cupferron, as reagents in chemical analysis, illustrating the compound′s adaptability and utility in analytical chemistry (Shendrikar, 1969).


Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Oral - Carc. 1B - Eye Irrit. 2 - Muta. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Gravimetric determination of beryllium with cupferron.
Das J and Baneerjee S.
Fresenius' Zeitschrift fur Analytische Chemie, 189(2), 183-187 (1962)
On the radiomimetic effects of cupferron and potassium cyanide.
Kihlman BA.
The Journal of Biophysical and Biochemical Cytology, 5(2), 351-353 (1959)
Preparation of Pb(Zr,Ti)03 Through the Use of Cupferron.
Kakegawa K, et al.
Journal of the American Chemical Society, 67(1) (1984)
Simultaneous adsorptive stripping voltammetric measurements of trace chromium, uranium, and iron in the presence of cupferron.
Wang J, et al.
Electroanalysis, 9(16), 1247-1251 (1997)
Moumita Ghosh et al.
Journal of nanoscience and nanotechnology, 4(1-2), 136-140 (2004-04-29)
ZnO nanoparticles have been synthesized from the cupferron complex by a solvothermal route in toluene solution. The nanoparticles have been prepared in the presence of various capping agents, of which the best results were obtained with tri-n-octylphosphine oxide, polyethylene glycol

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