P4380
Protamine sulfate
powder
Synonym(s):
Salmine, Salmine from salmon
Sign Into View Organizational & Contract Pricing
All Photos(2)
About This Item
Recommended Products
product name
Protamine sulfate salt from salmon, Grade II
biological source
fish (salmon)
Quality Level
type
Grade II
form
powder
color
white to off-white
solubility
6 M HCl: 25 mg/mL, clear, colorless to light yellow
Looking for similar products? Visit Product Comparison Guide
General description
Protamine sulfate (PS), a polycationic, positively charged protein is mostly made up of poly(l-arginine). It is obtained from salmon sperm protein.
Application
Protamine sulfate salt from salmon has been used in the generation of protamine silica nanocomposites.
May be used for the removal of DNA from protein samples or for the purification of DNA binding proteins. It may be used as an alternative to polybrene in retroviral-mediated gene transfer.
Protamine in the form of solid lipid nanoparticles (SLN) promoted transfection with plasmid DNA more efficiently and with less cytotoxicity than comparable SLNs composed of Esterquat-1.
Protamine in the form of solid lipid nanoparticles (SLN) promoted transfection with plasmid DNA more efficiently and with less cytotoxicity than comparable SLNs composed of Esterquat-1.
Protamine in the form of solid lipid nanoparticles (SLN) promoted transfection with plasmid DNA more efficiently and with less cytotoxicity than comparable SLNs composed of Esterquat-1.
Biochem/physiol Actions
Protamine sulfate is highly preferred in cardiovascular surgical procedures to reverse the anticoagulant properties of heparin. It is used for biomedical and biotechnological applications due to its biodegradablity.
Protamine sulfate is a small cationic protein that binds and precipitates DNA. Neutralizes the anticoagulant activity of heparin. Inhibits lipoprotein lipase.
Quality
May contain insolubles as well as histones.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Customers Also Viewed
Jacob F Warner et al.
Methods in molecular biology (Clifton, N.J.), 1128, 211-221 (2014-02-26)
The Hedgehog pathway has been shown to be an important developmental signaling pathway in many organisms (Ingham and McMahon. Genes Dev 15:3059-3087, 2001). Recently that work has been extended to developing echinoderm embryos (Walton et al. Dev Biol 331(1):26-37, 2009).
Protamine-templated biomimetic hybrid capsules: efficient and stable carrier for enzyme encapsulation
Zhang Y, et al.
Chemistry of Materials, 20(3), 1041-1048 (2007)
Drug-induced pulmonary disease
Murray and Nadel's Textbook of Respiratory Medicine, 1275-1294 (2016)
Blood Component and Pharmacologic Therapy for Hemostatic Disorders
Consultative Hemostasis and Thrombosis, 540-572 (2019)
Chitkala Satyanarayana et al.
BMC cancer, 4, 26-26 (2004-06-23)
We determined the effect of andrographolide and one of its novel semi-synthetic analog, DRF 3188, on the cell cycle of MCF 7 breast cancer cells. The effect of the compounds on cell cycle was determined using FACS and western blot
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service