Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

SMB01360

Sigma-Aldrich

1-MethylpseudoUridine

≥98% (HPLC)

Synonym(s):

1-Methyl-5-β-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione, N1-Methylpseudouridine

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C10H14N2O6
CAS Number:
13860-38-3
Molecular Weight:
258.23
MDL number:
MFCD10687017
UNSPSC Code:
41106305
NACRES:
NA.21

Quality Level

100

Assay

≥98% (HPLC)

form

solid

storage temp.

2-8°C

InChI

1S/C10H14N2O6/c1-12-2-4(9(16)11-10(12)17)8-7(15)6(14)5(3-13)18-8/h2,5-8,13-15H,3H2,1H3,(H,11,16,17)/t5-,6-,7-,8+/m1/s1

InChI key

UVBYMVOUBXYSFV-XUTVFYLZSA-N

General description

A key aspect of COVID-19 mRNA vaccines is the use of the modified nucleobase Methylpseudouridine to increase their effectiveness. The modified nucleobase helps cloak mRNA vaccines from the immune system, limiting their undesired immune stimulation, and in certain circumstances may also enhance the synthesis of antigens.

Application

Vaccine development

Other Notes

For additional information on our range of Biochemicals, please complete this form.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCW0824
MKCR3211

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service