SML3740
PY-60
≥98% (HPLC)
Synonym(s):
5-Phenyl-N-[3-(2-thiazolyl)propyl]-3-isoxazolecarboxamide
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About This Item
Empirical Formula (Hill Notation):
C16H15N3O2S
CAS Number:
Molecular Weight:
313.37
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.21
Quality Level
Assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
Biochem/physiol Actions
PY-60 is a potent and specific activator of the transcriptional coactivator Yes-associated protein 1 (YAP) signaling. It stimulates YAP-dependent expansion of epidermal keratinocytes in mouse. PY-60 binds directly to annexin A2 (ANXA2) causing its liberation and YAP activation.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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