57600
Interleukin-2 human
recombinant, expressed in E. coli, ~10000 U/mL
Synonym(s):
IL-2, TCGF, hIL-2
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About This Item
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Biochem/physiol Actions
Promotes the growth of IL-2 dependent lymphocytes. Amino acid sequence of IL-2.
Packaging
One vial contains 10′000 Units
Caution
Stable at −20 °C; prepare appropriate aliquots and avoid repeated freezing and thawing, since aggregation may occur resulting in apparent loss of activity.
Unit Definition
1 U corresponds to the unit activity in the colorimetric MTT-assay with CTLL-2 cells.
Physical form
Clear; colorless solution in Dulbecco-PBS; containing 1 mg BSA/mL.
Other Notes
Sales restrictions may apply.
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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K A Smith
Annual review of immunology, 2, 319-333 (1984-01-01)
S Gillis et al.
Journal of immunology (Baltimore, Md. : 1950), 120(6), 2027-2032 (1978-06-01)
Several soluble factors have recently been associated with the proliferation and differentiation of thymus-derived lymphocytes. One of these factors present in medium conditioned by T cell mitogen-stimulated lymphocytes has the ability to promote the long-term culture of normal and antigen-specific
R J Robb et al.
Proceedings of the National Academy of Sciences of the United States of America, 81(20), 6486-6490 (1984-10-01)
Human interleukin 2 was separated into multiple molecular forms by selective immunoaffinity chromatography and chromatofocusing. For the most part, this heterogeneity was attributed to variations in glycosylation of the threonine residue in position 3 of the polypeptide chain. The various
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