55467-U
Discovery® Glycan solid phase extraction (SPE) Cartridge
bed wt. 250 mg, volume 3 mL, pk of 54
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About This Item
UNSPSC Code:
41115712
NACRES:
NB.21
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product name
Discovery® Glycan SPE Tube, bed wt. 250 mg, volume 3 mL, pk of 54
material
PE frit
polypropylene
Quality Level
composition
bed wt., 250 mg
packaging
pk of 54
technique(s)
solid phase extraction (SPE): suitable
volume
3 mL
impurities
<5% Water content
matrix
polyamide resin base material
matrix active group
amide, poly- phase
particle size
50-160 μm
pH range
4.5-7.5(surface pH)
bulk density
0.2‑0.3 g/mL
separation technique
reversed phase
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General description
Retention Mechanism: Reversed-phase
Sample Matrix Compatibility: Aqueous or methanolic solutions
Sample Matrix Compatibility: Aqueous or methanolic solutions
- Polyamide Resin: Particle Size: 50-160 μm, Surf pH: 4.5-7.5, Density: 0.2-0.3 cm3/g, Water Content: < 5 %
- Useful for extracting gylcans from aqueous solutions.
- Used to adsorb polar compounds (-OH groups, esp. phenolic compounds) from aqueous or methanolic solutions under the reversed-phase mechanism through strong hydrogen bonding between compound hydroxyl groups and amide groups of the resin
- Also may be used for the extraction of tannins, chlorophyll, humic acid, pharmacologically active terpenoids, flavanoids, gallic acid, catechol A, protocatechuic acid, phloroglucinol, aromatic carboxylic acids, and nitroaromatic compounds
- Irreversibly retains quinones.
Legal Information
Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Qi Gu et al.
Methods in molecular biology (Clifton, N.J.), 1758, 129-138 (2018-04-22)
Bioprinting provides an opportunity to produce three-dimensional (3D) tissues for biomedical research and translational drug discovery, toxicology, and tissue replacement. Here we describe a method for fabricating human neural tissue by 3D printing human neural stem cells with a bioink
Tongqing Zhou et al.
Immunity, 48(3), 500-513 (2018-03-20)
Virtually the entire surface of the HIV-1-envelope trimer is recognized by neutralizing antibodies, except for a highly glycosylated region at the center of the "silent face" on the gp120 subunit. From an HIV-1-infected donor, #74, we identified antibody VRC-PG05, which
Chiara Setti et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 130, 71-82 (2018-06-22)
Emulsions are known to be effective carriers of hydrophobic drugs, and particularly injectable emulsions have been successfully implemented for in vivo controlled drug release. Recently, high internal phase emulsions have also been used to produce porous polymeric templates for pharmaceutical
Kaijie Xiao et al.
Rapid communications in mass spectrometry : RCM, 32(2), 142-148 (2017-11-07)
Most of the current popular tandem mass spectrometers have the capability of resolving the primary structures (monosaccharide composition, sequence and linkage) of N-glycans; however, compositions or putative structures have mostly been reported so far. Identification and visualization tools of N-glycans
Seok-Ho Yu et al.
The Journal of biological chemistry, 293(37), 14534-14544 (2018-07-28)
Deficiency in subunits of the conserved oligomeric Golgi (COG) complex results in pleiotropic defects in glycosylation and causes congenital disorders in humans. Insight regarding the functional consequences of this defective glycosylation and the identity of specific glycoproteins affected is lacking.
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