L8384
Linoleic Acid-Albumin from bovine serum albumin
γ-irradiated, lyophilized powder, BioReagent, suitable for cell culture
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About This Item
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biological source
bovine plasma
Quality Level
description
Contains 1.1-2.3 moles linoleic acid per mole BSA
sterility
γ-irradiated
product line
BioReagent
form
lyophilized powder
technique(s)
cell culture | mammalian: suitable
impurities
≤50 EU/mg endotoxin
solubility
water: 10 mg/mL, clear to hazy, colorless to light yellow
storage temp.
2-8°C
General description
Linoleic acid is an essential and highly consumed polyunsaturated fatty acid (PUFA). Albumin is a globular protein. Bovine serum albumin (BSA) is composed of a single polypeptide chain and cross-linked cysteine disulfide bridges. BSA is heart-shaped and is made up of three homologous domains I-III and each domain has two subdomains A and B.
Application
Linoleic Acid-Albumin from bovine serum albumin has been used: in cell culture and to study its effects on the human colonic adenocarcinoma cell line. It has also been used in the in vitro culture (IVC) of cow embryos/zygotes. The binding of linoleic acid to BSA improves its stability and solubility in culture media.
Biochem/physiol Actions
Linoleic acid plays a role in maintaining the transdermal water barrier in epidermis. Serum albumin constitutes about 52-62% of the total water-soluble fraction proteins in the blood plasma.
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Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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