07-363
Anti-AMPK α2 Antibody
Upstate®, from rabbit
Synonym(s):
AMP-Activated Protein Kinase, AMPK
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human, rat
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... PRKAA2(5563)
Specificity
Recognizes AMP-Activated Protein Kinase alpha2 (AMPKα2).
Immunogen
peptide corresponding to amino acids 353-367 (C-DDSAMHIPPGLKPHP) of human AMP-Activated Protein Kinase alpha2 (AMPKalpha2) catalytic subunit
Application
Detect AMPK α2 using this Anti-AMPK α2 Antibody validated for use in WB.
Research Category
Signaling
Signaling
Research Sub Category
Insulin/Energy Signaling
Insulin/Energy Signaling
Quality
routinely evaluated by immunoblot in a rat liver preparation
Target description
~63 kDa
Physical form
Format: Purified
Protein A Purified immunoglobulin in 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative.
Protein A purified
Storage and Stability
Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Analysis Note
Control
Rat liver preparation
Rat liver preparation
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Miki Tadaishi et al.
American journal of physiology. Endocrinology and metabolism, 300(2), E341-E349 (2010-11-26)
There are three isoforms of peroxisome proliferator-activated receptor-γ coactivator 1α (PGC-1α) mRNA, which promotes mitochondrial biogenesis in skeletal muscles. Compared with PGC-1α-a mRNA, PGC-1α-b or PGC-1α-c mRNA is transcribed by a different exon 1 of the PGC-1α gene. In this
TBC1D1 regulates insulin- and contraction-induced glucose transport in mouse skeletal muscle.
An, D; Toyoda, T; Taylor, EB; Yu, H; Fujii, N; Hirshman, MF; Goodyear, LJ
Diabetes null
TBC 11251. IPI 1040.
Drugs in R&D, 2(1), 38-39 (1999-12-28)
Transcriptome and translational signaling following endurance exercise in trained skeletal muscle: impact of dietary protein.
Rowlands, DS; Thomson, JS; Timmons, BW; Raymond, F; Fuerholz, A; Mansourian, R; Zwahlen et al.
Physiological Genomics null
B J Michell et al.
The Journal of biological chemistry, 271(45), 28445-28450 (1996-11-08)
The 5'-AMP-activated protein kinase (AMPK) mediates several cellular responses to metabolic stress. Rat liver contains at least two isoforms of this enzyme, either alpha1 or alpha2 catalytic subunits together with beta and gamma noncatalytic subunits in a trimeric complex. The
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