07964
Methoxypolyethylene glycol amine
750
Synonym(s):
mPEG-NH2, O-(2-Aminoethyl)-O′-methylpolyethylene glycol, Aminopolyethylene glycol monomethyl ether, Methoxypolyoxyethylene amine
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Linear Formula:
H2NCH2CH2(OCH2CH2)nOCH3
CAS Number:
MDL number:
UNSPSC Code:
12162002
NACRES:
NA.22
Recommended Products
Quality Level
form
solid
color
white to yellow
InChI
1S/C3H9NO/c1-5-3-2-4/h2-4H2,1H3
InChI key
ASUDFOJKTJLAIK-UHFFFAOYSA-N
Looking for similar products? Visit Product Comparison Guide
Application
Methoxypolyethylene glycol amine can:
- Form dendritic micelles to enhance the solubility of hydrophobic compounds.
- Conjugate with an anticancer drug methotrexate (MTX) to form MTX-PEG with potential application as drug carriers.
- Couple with polyethylenimine (PEI) to form graft copolymers which can be used as nonviral gene vectors.
Other Notes
Oligomer used to prepare PEG-ylated conjugates having the advantage of reduced immunogenicity and increased serum half life
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Customers Also Viewed
Polyethylene glycol-polyamidoamine dendritic micelle as solubility enhancer and the effect of the length of polyethylene glycol arms on the solubility of pyrene in water.
Yang H, et al.
Journal of Colloid and Interface Science, 273(1), 148-154 (2004)
Polyethylene Glycol Conjugates of Methotrexate Varying in Their Molecular Weight from MW 750 to MW 40000: Synthesis, Characterization, and Structure- Activity Relationships in Vitro and in Vivo.
Riebeseel K, et al.
Bioconjugate Chemistry, 13(4), 773-785 (2002)
M Yokoyama et al.
Bioconjugate chemistry, 3(4), 295-301 (1992-07-01)
Adriamycin, a hydrophobic anticancer drug, was conjugated with poly(ethylene oxide)-poly(aspartic acid) block copolymers composed of various lengths of each block copolymer segment ranging from 1000 to 12,000 in molecular weight and from 10 to 80 units, respectively. Conjugation was achieved
T.P. Kogan
Synthetic Communications, 22, 2417-2417 (1992)
Effect of polyethylene glycol on gene delivery of polyethylenimine.
Sung SJ, et al.
Biological & Pharmaceutical Bulletin, 26(4), 492-500 (2003)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service