648471
Trolox
A cell-permeable, water-soluble derivative of vitamin E with antioxidant properties. Prevents peroxynitrite-mediated oxidative stress and apoptosis in rat thymocytes.
Synonym(s):
Trolox, 6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic Acid
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About This Item
Empirical Formula (Hill Notation):
C14H18O4
CAS Number:
Molecular Weight:
250.29
MDL number:
UNSPSC Code:
12352205
Recommended Products
Assay
≥98% (titration)
form
powder
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
white to off-white
white to pale green
white to pale yellow
solubility
water: 0.5 mg/mL (slightly soluble)
ethanol: 150 mg/mL
methanol: soluble
shipped in
ambient
storage temp.
2-8°C
InChI
1S/C14H18O4/c1-7-8(2)12-10(9(3)11(7)15)5-6-14(4,18-12)13(16)17/h15H,5-6H2,1-4H3,(H,16,17)
InChI key
GLEVLJDDWXEYCO-UHFFFAOYSA-N
General description
A cell-permeable, water-soluble derivative of vitamin E with antioxidant properties. Prevents peroxynitrite-mediated oxidative stress and apoptosis in rat thymocytes.
A cell-permeable, water-soluble derivative of vitamin E with potent antioxidant properties. Prevents peroxynitrite-mediated oxidative stress and apoptosis in rat thymocytes.
Application
- Structural characterization of peroxyl radical oxidative products of antioxidant peptides from hydrolyzed proteins.: This study highlights the application of Trolox in understanding the oxidative modifications of antioxidant peptides, which could help in the development of more effective antioxidative therapies and supplements (Esfandi et al., 2024).
- Extraction of bioactive compounds from pecan nutshell: An added-value and low-cost alternative for an industrial waste.: Trolox is utilized to evaluate the antioxidant capacity of bioactive extracts from pecan shells, presenting a sustainable approach to utilizing agricultural waste (Cardona Jimenez et al., 2024).
- Investigation into the role of carboxylic acid and phenolic hydroxyl groups in the plant biostimulant activity of a humic acid purified from an oxidized sub-bituminous coal.: Utilizing Trolox equivalent antioxidant capacity (TEAC) assay, this research explores the bio-stimulatory properties of humic substances, enhancing our understanding of their role in agriculture (Lamar et al., 2024).
Warning
Toxicity: Harmful (C)
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Ethanol stock solutions are stable for up to 1 month at -20°C.
Other Notes
Salgo, M.G. and Pryor, W.A. 1996. Arch. Biochem. Biophys. 333, 482.
McClain, D.E., et al. 1995. FASEB J. 9, 1345.
Salgo, M.G., et al. 1995. Arch. Biochem. Biophys.322, 500.
McClain, D.E., et al. 1995. FASEB J. 9, 1345.
Salgo, M.G., et al. 1995. Arch. Biochem. Biophys.322, 500.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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