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1.09844

Sigma-Aldrich

Eosin Y-solution 0.5% aqueous

for microscopy

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About This Item

UNSPSC Code:
41116124
NACRES:
NA.41

Quality Level

form

liquid

IVD

for in vitro diagnostic use

density

1.00 g/cm3

application(s)

clinical testing
diagnostic assay manufacturing
hematology
histology

storage temp.

15-25°C

General description

Eosin Y-solution 0.5% aqueous - for microscopy, is used for human-medical cell diagnosis and serves the histological and clinico-cytological investigation of sample material of human origin. The hematoxylin and eosin (H&E) staining method is the method most frequently used for the staining of histology material. This Eosin Y-solution is a 0.5% aqueous staining solution, that can be used e. g. for the histological staining of instantaneous sections.The staining mechanism behind the H&E staining is a physico-chemical process. In the first step, the positively charged nuclear dye (hematoxylin) Mayer′s hemalum solution for microscopy (Produt number 1.09249) or Hematoxylin solution modified acc. to Gill III (Product number 1.05174) binds to the negatively charged phosphate groups of the nucleic acid of the cell nucleus. The nuclei will be dyed dark blue to dark violet. The second step is the counterstaining with negatively charged anionic Eosin Y, a xanthene dye. Eosin binds to the positively charged plasma proteins. Cytoplasm and intercellular substances are stained pink to red, while erythrocytes will appear with yellow to orange color.
The 500ml bottle provides 1500 stainings. It is an IVD registered product and CE certified, thus can be used for clinical diagnostic purposes. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.

Analysis Note

Suitability for microscopy (Tissue section): passes test
nuclei: dark blue to dark violet
Cytoplasm: pink to red
intercellular substances: pink to red
Erythrocytes: yellow to orange

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Skin Sens. 1

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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