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Key Documents

802115

Sigma-Aldrich

Polycaprolactone dimethacrylate

average Mn 800

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About This Item

Linear Formula:
(C6H10O2)nC12H18O5
UNSPSC Code:
12162002
NACRES:
NA.23

form

liquid

Quality Level

mol wt

average Mn 800

refractive index

n20/D 1.471

density

1.094 g/mL at 25 °C

storage temp.

−20°C

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Application

Polycaprolactone is a biodegradable polymer commonly used in biomedical applications. A light-activated Polycaprolactone dimethacrylate gel was used for the sustained delivery of an anti-VEGF antibody.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3


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Puneet Tyagi et al.
Molecular pharmaceutics, 10(8), 2858-2867 (2013-06-06)
A light-activated polycaprolactone dimethacrylate (PCM) and hydroxyethyl methacrylate (HEMA) based gel network was developed to sustain the release of stable, active bevacizumab (an anti-VEGF antibody used to treat choroidal neovascularization) and used to assess sustained ex vivo delivery in rabbit

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