Establishment of a human iPSC line (IISHDOi001-A) from a patient with McArdle disease.

Establishment of a human iPSC line (IISHDOi001-A) from a patient with McArdle disease.

Stem cell research (2017-09-20)

María Del Carmen Ortuño-Costela, Nathalie Rodríguez-Mancera, Marta García-López, Francisco Zurita-Díaz, Ana Moreno-Izquierdo, Alejandro Lucía, Miguel Ángel Martín, Rafael Garesse, M Esther Gallardo

PMID28925366

RÉSUMÉ

Human iPSC line IISHDOi001-A was generated from fibroblasts of a patient with McArdle disease harbouring the mutation, c.148C>T; p.Arg50Ter, in the PYGM gene. Reprogramming factors Oct3/4, Sox2, Klf4, and c-Myc were delivered using Sendai virus.