- A facile approach to the synthesis of chiral 2-substituted benzofurans.
A facile approach to the synthesis of chiral 2-substituted benzofurans.
The Journal of organic chemistry (2007-04-11)
Lidia De Luca, Giampaolo Giacomelli, Giammario Nieddu
PMID17419648
RÉSUMÉ
An effective route to chiral optically active 2-substituted benzofurans directly from carboxylic acids is reported. This procedure, which allows the preparation of alpha-alkyl-2-benzofuranmethanamines from N-protected alpha-amino acids without sensible racemization phenomena, proceeds in good yields under mild conditions with the help of microwave irradiation.
MATÉRIAUX
Référence du produit
Marque
Description du produit
Référence
Conditionnement
Disponibilité
Prix
Quantité