Synthesis of deuterium-labelled isotopomer of deferasirox.

Synthesis of deuterium-labelled isotopomer of deferasirox.

Journal of labelled compounds & radiopharmaceuticals (2015-02-19)

Freddy H Havaldar, Bhushan Vasant Dabholkar, Ganesh Baban Mule, Suhas Kulkarni

RÉSUMÉ

A d4 -labeled isotopomer of deferasirox was synthesized as internal standard for use in a LC/mass spectroscopy (MS)/MS method developed for the simultaneous quantitative determination of deferasirox in human serum. d4 -deferasirox was synthesized from d8 -toluene.

MATÉRIAUX

Référence du produit

Marque

Description du produit

434388

Sigma-Aldrich

Toluène-d₈, 99.6 atom % D

151998

Sigma-Aldrich

Toluène-d₈, 99 atom % D

471399

Sigma-Aldrich

Toluène-d₈, 99 atom % D, contains 0.03 % (v/v) TMS

233382

Sigma-Aldrich

Toluène-d₈, "100%", 99.96 atom % D