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  • Stabilization and enhanced reactivity of actinorhodin polyketide synthase minimal complex in polymer-nucleotide coacervate droplets.

Stabilization and enhanced reactivity of actinorhodin polyketide synthase minimal complex in polymer-nucleotide coacervate droplets.

Chemical communications (Cambridge, England) (2012-10-27)
John Crosby, Tom Treadwell, Michelle Hammerton, Konstantinos Vasilakis, Matthew P Crump, David S Williams, Stephen Mann
RÉSUMÉ

Compartmentalization of the minimal complex of actinorhodin polyketide synthase in coacervate liquid droplets produces enhanced yields of shunt polyketides under conditions of low and high ionic strength.

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Poly(diallyldimethylammonium chloride) solution, average Mw 200,000-350,000 (medium molecular weight), 20 wt. % in H2O
Sigma-Aldrich
Poly(diallyldimethylammonium chloride) solution, average Mw <100,000 (very low molecular weight), 35 wt. % in H2O
Sigma-Aldrich
Poly(diallyldimethylammonium chloride) solution, 20 wt. % in H2O
Sigma-Aldrich
Poly(diallyldimethylammonium chloride) solution, average Mw 400,000-500,000 (high molecular weight), 20 wt. % in H2O