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Use of the loop diuretic torsemide in three dogs with advanced heart failure.

Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology (2011-10-28)
Mark A Oyama, Gordon D Peddle, Caryn A Reynolds, Gretchen E Singletary
RÉSUMÉ

Diuretics are a mainstay of therapy in dogs with heart failure. In dogs with advanced heart failure, moderate to high doses of loop diuretics such as furosemide are used with diminishing effects as profound activation of neuroendocrine systems promote signs of congestive heart failure. The loop diuretic torsemide has several characteristics that make it suitable for treatment of advanced heart failure including longer half-life, increased potency of diuretic action, and anti-aldosterone effects. This case report details the administration of torsemide in 3 dogs with advanced heart failure and apparent furosemide resistance.

MATÉRIAUX
Référence du produit
Marque
Description du produit

Sigma-Aldrich
Torsemide, ≥98% (HPLC), solid
Torsemide, European Pharmacopoeia (EP) Reference Standard
Torsemide, European Pharmacopoeia (EP) Reference Standard