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Merck

A substrate-independent approach for bactericidal surfaces.

ACS applied materials & interfaces (2010-04-02)
W C E Schofield, J P S Badyal
RÉSUMÉ

Existing methods for imparting antibacterial performance to solid surfaces tend to either be substrate-specific or rely upon leaching modes of action that cause ecological damage. An alternative approach is outlined comprising plasmachemical functionalization of solid surfaces with poly(4-vinyl pyridine) moieties and their subsequent activation (quaternization) with bromobutane to yield bactericidal activity. These bioactive surfaces can be applied to a host of different substrate materials and are easily regenerated by rinsing in water.

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Sigma-Aldrich
1-Bromobutane, ReagentPlus®, 99%
Supelco
1-Bromobutane, analytical standard