SAB4200762

Anti-Opsin antibody, Mouse monoclonal

clone RET-P1, purified from hybridoma cell culture

• Synonyme(s) : Anti-Opsin 2, Anti-Rhodopsin
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: mouse
• Niveau de qualité: 200
• Forme d'anticorps: purified from hybridoma cell culture
• Type de produit anticorps: primary antibodies
• Clone: RET-P1, monoclonal
• Forme: buffered aqueous solution
• Poids mol.: ~39 kDa
• Espèces réactives: avian, bovine, fish, mouse, rat, human, amphibian, turtle, rabbit
• Concentration: ~1 mg/mL
• Technique(s): ELISA: suitable; immunoblotting: 2-4 μg/mL using human retinoblastoma Y79 cell line extract. ; immunofluorescence: suitable; immunohistochemistry: 5-10 μg/mL using rat eye frozen sections.; radioimmunoassay: suitable
• Isotype: IgG1
• Numéro d'accès UniProt: P08100
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: rat ... Rho(24717)

Description

Description générale

Anti-Opsin antibody, Mouse monoclonal (rhodopsin) (mouse IgG1 isotype) is derived from the RET-P1 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB/C mice immunized with rat retinal membranes. Opsin is also called as rhodopsin protein, members of the G-protein coupled receptor (GPCR) superfamily. Opsin comprises >95% of the rod outer segments (ROS) intrinsic membrane and consists of a protein moiety - an opsin - and a non-protein moiety - the chromophore retinal.

Application

Anti-Opsin antibody has been used in

• immunoblotting
• immunofluorescence
• immunohistochemistry
• enzyme linked immunosorbent assay (ELISA)
• radioimmuno assay (RIA)

Actions biochimiques/physiologiques

Opsin is an essential molecules for mediating the ability of animals to detect and use light for diverse biological functions. Mutations in the opsin (rhodopsin) gene are linked to retinitis pigmentosa (RP), a disease characterized by retinal degeneration resulting in reduced peripheral vision and night blindness.

Autres remarques

rat retinal membranes

Forme physique

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable