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Key Documents

S1439

Sigma-Aldrich

Monoclonal Anti-SERCa2 ATPase antibody produced in mouse

clone IID8

Synonyme(s) :

Monoclonal Anti-Sarcoplasmic or Endoplasmic Reticulum Ca2+ ATPase

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About This Item

Numéro MDL:
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Forme d'anticorps

purified from hybridoma cell culture

Niveau de qualité

Type de produit anticorps

primary antibodies

Clone

IID8, monoclonal

Espèces réactives

bovine, canine, rat, human, pig, rabbit

Technique(s)

immunocytochemistry: suitable
immunohistochemistry (frozen sections): 1:500
indirect immunofluorescence: suitable
western blot: 1:500-1:5,000

Numéro d'accès UniProt

Conditions d'expédition

dry ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... ATP2A2(488)
rat ... Atp2a2(29693)

Immunogène

purified canine cardiac sarcoplasmic reticulum.

Forme physique

Supplied as a solution in PBS containing 0.05% sodium azide.

Autres remarques

Not suitable for immunoblotting in rat SERCA2.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Produit(s) apparenté(s)

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

nwg

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Ning Li et al.
Traffic (Copenhagen, Denmark), 18(4), 232-241 (2017-02-06)
Darier's disease (DD) is an autosomal dominantly inherited skin disorder caused by mutations in sarco/endoplasmic reticulum Ca2+ -ATPase 2 (SERCA2), a Ca2+ pump that transports Ca2+ from the cytosol to the endoplasmic reticulum (ER). Loss of desmosomes and keratinocyte cohesion
Mirella Telles Salgueiro Barboni et al.
Progress in retinal and eye research, 95, 101137-101137 (2022-11-21)
Duchenne muscular dystrophy (DMD) is caused by X-linked inherited or de novo DMD gene mutations predominantly affecting males who develop early-onset muscle degeneration, severely affecting their quality of life and leading to reduced life expectancy. DMD patients may also develop
Karolina Varga et al.
Cell calcium, 55(2), 78-92 (2014-01-21)
The expression of the plasma membrane Ca2+ ATPase (PMCA) isoforms is altered in several types of cancer cells suggesting that they are involved in cancer progression. In this study we induced differentiation of MCF-7 breast cancer cells by histone deacetylase
Victor Galvan-Alvarez et al.
Redox biology, 66, 102859-102859 (2023-09-05)
When high-intensity exercise is performed until exhaustion a "functional reserve" (FR) or capacity to produce power at the same level or higher than reached at exhaustion exists at task failure, which could be related to reactive oxygen and nitrogen species
Haibin Gong et al.
Experimental and therapeutic medicine, 12(3), 1355-1362 (2016-09-08)
The study was conducted to examine the effects of ICI 118,551 on the systolic function of cardiac muscle cells of rats in heart failure and determine the molecular mechanism of selective β2-adrenergic receptor (β2-AR) antagonist on these cells. The chronic

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